VWA1_MOUSE   Q8R2Z5


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UniProt:Q8R2Z5

Recommended name:von Willebrand factor A domain-containing protein 1

EC number:

Alternative names:(von Willebrand factor A domain-related protein)

Cleaved into:

GeneID:246228

Gene names  (primary ):Vwa1

Gene names  (synonym ):Warp

Gene names  (ORF ):

Length:415

Mass:44709

Sequence:MLFWTAFSMALSLRLALARSSIERGSTASDPQGDLLFLLDSSASVSHYEFSRVREFVGQLVATMSFGPGALRASLVHVGSQPHTEFTFDQYSSGQAIQDAIRVAPQRMGDTNTGLALAYAKEQLFAEEAGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTIFIVSTGRGNLLELLAAASAPAEKHLHFVDVDDLPIIARELRGSITDAMQPQQLHASEVLSSGFRLSWPPLLTADSGYYVLELVPSGKLATTRRQQLPGNATSWTWTDLDPDTDYEVSLLPESNVHLLRPQHVRVRTLQEEAGPERIVISHARPRSLRVSWAPALGPDSALGYHVQLGPLQGGSLERVEVPAGQNSTTVQGLTPCTTYLVTVTAAFRSGRQRALSAKACTASGARTRAPQSMRPEAGPREP

Tissue specificity:Expressed at high levels in the chondrocytes. Detected in the vasculature of neural tissues, in basement membrane structures of the peripheral nervous system, in the apical ectodermal ridge of developing limb buds, and in skeletal and cardiac muscle (at protein level). {ECO:0000269|PubMed:12062410, ECO:0000269|PubMed:18314316}.

Induction:

Developmental stage:Restricted to the presumptive articular cartilage zone prior to joint cavitation and to the articular cartilage and fibrocartilaginous elements in the joint, spine and sternum during embryonic development. Detected from 9.5 dpc in the vasculature of the central nervous system. At 16.5 dpc, present in intervertebral disks of the spinal cord, lip epithelium and developing oral and tooth germ epithelia (at protein level). {ECO:0000269|PubMed:16407285, ECO:0000269|PubMed:18314316, ECO:0000269|PubMed:18757743}.

Protein families:


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