RSPRY_MOUSE Q8BVR6
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UniProt:Q8BVR6
Recommended name：RING finger and SPRY domain-containing protein 1
EC number：
Alternative names：
Cleaved into：
GeneID：67610
Gene names (primary )：Rspry1
Gene names (synonym )：Kiaa1972
Gene names (ORF )：
Length：576
Mass：64322
Sequence：MIVFGWAVFLASRSLGQGLLLTLEEHIAHLLGTTGATATMGNSCICRDDSGAEDNVDTHQQQAENSTVPTADSRSQPRDPVRPPRRGRGPHEPRRKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLDVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLNGEVACQDSGHPAKHRNTSAVLGCLAEKLAGPASIGLLSPGILEYLLQCLKLQSHPTVMLFALIALEKFAQTSENKLTISESSISDRLVTLELWADDPDYLKRQVGFCAQWSLDNLFLKEGRQLTYEKVDLNNIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDTGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHVHPCWKEGDTVGFLLDLNEKQMIFFLNGNQLPPEKQVFSSTVSGFFAAASFMSYQQCEFNFGARPFKYPPSMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLETCPLCRKEIVSRIRQISHIS
Tissue specificity：Expressed in embryonic bone during primary endochondral ossification. Strong localization is observed in the perichondrium and periostium (at protein level). Also expressed in embryonic and postnatal brain and craniofacial tissues. Expressed in skeletal muscles (PubMed:26497270). {ECO:0000269|PubMed:26365341, ECO:0000269|PubMed:26497270}.
Induction：Up-regulated in response to denervation-induced skeletal muscle atrophy. Induced by MYOD1. {ECO:0000269|PubMed:26497270}.
Developmental stage：Shows relatively low expression levels in proliferating myoblasts. Expression peaks at around day 1 of differentiation into myotubes and decreases again by day 10, when assayed in C2C12 cell line (at protein level). {ECO:0000269|PubMed:26497270}.
Protein families：