VATC2_MOUSE Q99L60
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UniProt:Q99L60
Recommended name：V-type proton ATPase subunit C 2
EC number：
Alternative names：(V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)
Cleaved into：
GeneID：68775
Gene names (primary )：Atp6v1c2
Gene names (synonym )：Atp6c2
Gene names (ORF )：
Length：427
Mass：48350
Sequence：MSEFWLISAPGDKENLQALERMNNVTSKSNLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIKRMAQSVVEVMEDSKGKAHETLLANGVDLTSFVTHFEWDMAKYPAKQPLVSVVDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKRSTGNLFTRTLSDIVSKEDFVLDSEYLITLLVIVPKSSFAQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREFYYDEKEIKREREEMTRLLSDKKQQYPTSCVALKKGSATYRDHKVKVAPLGNPARPAAGQTDRDRESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREVLNSVFRHLDEVAAASILDASVEIPGLQLSNQDYFPYVYFHIDLSLLD
Tissue specificity：Predominantly expressed in the lung and kidney. Isoform 1 is lung-specific while isoform 3 is a kidney-specific isoform. Isoform 1 is localized in the lamellar bodies of type II alveolar cells. Isoform 2 is strongly expressed in the cortical and medulla collecting ducts and is found in the plasma membranes of renal alpha and beta intercalated cells. {ECO:0000269|PubMed:12527205, ECO:0000269|PubMed:12947086}.
Induction：
Developmental stage：Significant expression seen at 17 dpc and not earlier. {ECO:0000269|PubMed:12527205}.
Protein families：V-ATPase C subunit family