SUV92_MOUSE   Q9EQQ0


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UniProt:Q9EQQ0

Recommended name:Histone-lysine N-methyltransferase SUV39H2

EC number:EC 2.1.1.355

Alternative names:(Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)

Cleaved into:

GeneID:64707

Gene names  (primary ):Suv39h2

Gene names  (synonym ):

Gene names  (ORF ):

Length:477

Mass:54098

Sequence:MATARAKARGSEAGARCHRAPGPPPRPKARRTARRRRAETLTARRSRPSAGERRAGSQRAWSGAPRAAVFGDECARGALFKAWCVPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVAKGVEYYLVKWKGWPDSTNTWEPLRNLRCPQLLRQFSDDKKTYLAQERKCKAVNSKSLQPAIAEYIVQKAKQRIALQRWQDYLNRRKNHKGMIFVENTVDLEGPPLDFYYINEYRPAPGISINSEATFGCSCTDCFFDKCCPAEAGVVLAYNKKQQIKIQPGTPIYECNSRCRCGPECPNRIVQKGTQYSLCIFKTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGEASSDSIDHSPAKKRVRTQCKCGAETCRGYLN

Tissue specificity:Testis specific; predominant expression in type B spermatogonia and preleptotene spermatocytes.

Induction:

Developmental stage:Strong expression in early embryos with a peak at 10.5 dpc. Expression is down-regulated at 17.5 dpc, and is nearly absent during postnatal development. In adult testes, prominent expression in late but not early spermatocytes.

Protein families:Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily


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