SUV92_MOUSE Q9EQQ0
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UniProt:Q9EQQ0
Recommended name:Histone-lysine N-methyltransferase SUV39H2
EC number:EC 2.1.1.355
Alternative names:(Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)
Cleaved into:
GeneID:64707
Gene names (primary ):Suv39h2
Gene names (synonym ):
Gene names (ORF ):
Length:477
Mass:54098
Sequence:MATARAKARGSEAGARCHRAPGPPPRPKARRTARRRRAETLTARRSRPSAGERRAGSQRAWSGAPRAAVFGDECARGALFKAWCVPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVAKGVEYYLVKWKGWPDSTNTWEPLRNLRCPQLLRQFSDDKKTYLAQERKCKAVNSKSLQPAIAEYIVQKAKQRIALQRWQDYLNRRKNHKGMIFVENTVDLEGPPLDFYYINEYRPAPGISINSEATFGCSCTDCFFDKCCPAEAGVVLAYNKKQQIKIQPGTPIYECNSRCRCGPECPNRIVQKGTQYSLCIFKTSNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGEASSDSIDHSPAKKRVRTQCKCGAETCRGYLN
Tissue specificity:Testis specific; predominant expression in type B spermatogonia and preleptotene spermatocytes.
Induction:
Developmental stage:Strong expression in early embryos with a peak at 10.5 dpc. Expression is down-regulated at 17.5 dpc, and is nearly absent during postnatal development. In adult testes, prominent expression in late but not early spermatocytes.
Protein families:Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, Suvar3-9 subfamily