LBR_MOUSE Q3U9G9
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UniProt:Q3U9G9
Recommended name：Delta(14)-sterol reductase LBR (Delta-14-SR)
EC number：EC 1.3.1.70
Alternative names：(3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (Lamin-B receptor) (Sterol C14-reductase)
Cleaved into：
GeneID：98386
Gene names (primary )：Lbr
Gene names (synonym )：
Gene names (ORF )：
Length：626
Mass：71440
Sequence：MPSRKFVEGEVVRGRWPGSSLYYEVEILSHDNKSQLYTVKYKDGTELELKESDIKPLKSFKQRKSGSISSSPSRRRGSRSRSRSRSRSRSPGRAPKGSRRSVSASHEGDVKEKKEKEMRREILQVKLTPLVLKPFGNSVSVYNGEPEHMEKNATPYKDKQERIILSTEDRYIVTQYSLRPRREEVKAKEIESEEQNLVTKGPAPLGTFQVTTPQRKDLEFGGVPGAVLIMLGLPACVLLLLLQCRQKDPGLLHFPPPLPALHELWEPRVCGVYLLWFFVQALFHLLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWGVELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREELSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVDALWNEEALLTSMDIMHDGFGFMLAFGDLVWVPFTYSLQAFYLVSHPHDLSWPLASVIIALKLCGYVIFRCANSQKNAFRKNPTDPKLAHLKTIHTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHLLPYFYIIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY
Tissue specificity：Highly expressed in the testis and lung. Also expressed in the heart, ovary, kidney and liver. {ECO:0000269|PubMed:18785926}.
Induction：
Developmental stage：Strongly expressed in liver, skin, brain as well as in specific regions of the developing cartilage and bone in embryos. {ECO:0000269|PubMed:21327084}.
Protein families：ERG4/ERG24 family