PA24C_MOUSE Q64GA5
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UniProt:Q64GA5
Recommended name:Cytosolic phospholipase A2 gamma
EC number:EC 3.1.1.4
Alternative names:(cPLA2-gamma) (Cytosolic lysophospholipase) (Cytosolic lysophospholipid O-acyltransferase) (Phospholipase A2 group IVC)
Cleaved into:
GeneID:232889
Gene names (primary ):Pla2g4c
Gene names (synonym ):
Gene names (ORF ):
Length:597
Mass:67882
Sequence:MELSSGVCPATRLQEAEKAAVHKRSPKVLEALRKLNIQADQAPVIAVLGSGGGLRAHIACLGVLSELKELGLLDAVTYLAGVSGSTWALSSLYTKNGNMEGIEEELKHRYEKNEWDFHESLEKAIQASKRENYSLTDFWAYLIVSRQIRELQDSNLSSLKKQVEEGVLPYPIFAAIDEDLLADWRERKTQNSWFEFTPHHAGYPALGAYVPITEFGSRFENGKLVKSEPERDLTFLRGLWGSAFADIKEIKNYILNYFRNPFGKLKFIEGPVTYSEAPRMNVDAMLLDLVMAYFTDMNDPSIKDKLCALQQALGTETDEFGIEMAEIIQNWNETSAEKKEQFLDHLLDRFKKTQEDTTTYSLMNWNTGLVWDRCVFVNETRKCVSKWQWGTVYNFLYKHGKIADETMCSRELLHLVDAGFAINTPYPLVLPPVRETHLILSFDFSAGDPLETIRATADYCQRHEIPFPEVSEDQLKEWAKAPASCYVLRGETGPVVMHFTLFNKDNCGDDIETWRKKYGTVKLSDSYTPDLVRDLLRVSKENVKKNKINILSEMRKVAGNPGNIPRVNKEACLGDRVKDPQGSQTVEFKKSHNISKD
Tissue specificity:Highly expressed in ovary, where it localizes to oocytes in preantral and antral stage follicles (at protein level). Not detected in other tissues tested. {ECO:0000269|PubMed:15950603}.
Induction:
Developmental stage:Strongly expressed in oocytes at the germinal vesicle stage, and in zygotes (at protein level). Maternal expression persists in embryos at the 2-cell stage but then declines rapidly and is completely lost by the morula stage (at protein level). {ECO:0000269|PubMed:15950603}.
Protein families: