P63_MOUSE O88898
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UniProt:O88898
Recommended name:Tumor protein 63
EC number:
Alternative names:(p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L)
Cleaved into:
GeneID:22061
Gene names (primary ):Tp63
Gene names (synonym ):P63 P73l Tp73l Trp63
Gene names (ORF ):
Length:680
Mass:76789
Sequence:MNFETSRCATLQYCPDPYIQRFIETPAHFSWKESYYRSAMSQSTQTSEFLSPEVFQHIWDFLEQPICSVQPIELNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMDSRRNKQQRIKEEGE
Tissue specificity:Widely expressed, notably in thymus, prostate, placenta and skeletal muscle, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast and prostate express high levels of DeltaN-type isoforms. {ECO:0000269|PubMed:9774969}.
Induction:Induced by DNA damaging agents. {ECO:0000269|PubMed:11932750}.
Developmental stage:TA*-type isoforms are expressed from 7.5 dpc, prior to the onset of epithelial stratification, while DeltaN-type isoforms are expressed from 9.5 dpc. {ECO:0000269|PubMed:14729569}.
Protein families:P53 family