P63_MOUSE   O88898


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UniProt:O88898

Recommended name:Tumor protein 63

EC number:

Alternative names:(p63) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L)

Cleaved into:

GeneID:22061

Gene names  (primary ):Tp63

Gene names  (synonym ):P63 P73l Tp73l Trp63

Gene names  (ORF ):

Length:680

Mass:76789

Sequence:MNFETSRCATLQYCPDPYIQRFIETPAHFSWKESYYRSAMSQSTQTSEFLSPEVFQHIWDFLEQPICSVQPIELNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMDSRRNKQQRIKEEGE

Tissue specificity:Widely expressed, notably in thymus, prostate, placenta and skeletal muscle, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast and prostate express high levels of DeltaN-type isoforms. {ECO:0000269|PubMed:9774969}.

Induction:Induced by DNA damaging agents. {ECO:0000269|PubMed:11932750}.

Developmental stage:TA*-type isoforms are expressed from 7.5 dpc, prior to the onset of epithelial stratification, while DeltaN-type isoforms are expressed from 9.5 dpc. {ECO:0000269|PubMed:14729569}.

Protein families:P53 family


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