PHB2_MOUSE O35129
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UniProt:O35129
Recommended name:Prohibitin-2
EC number:
Alternative names:(B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity)
Cleaved into:
GeneID:12034
Gene names (primary ):Phb2
Gene names (synonym ):Bap Bcap37 Rea
Gene names (ORF ):
Length:299
Mass:33296
Sequence:MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
Tissue specificity:Widely expressed in different tissues. {ECO:0000269|PubMed:11302691, ECO:0000269|PubMed:15140878, ECO:0000269|PubMed:8070406}.
Induction:In B cells, expression is increased by CD40 engagement (at protein level). {ECO:0000269|PubMed:23241883}.
Developmental stage:Throughout gestation, highly expressed in brown fat, heart, liver, developing renal tubules and neurons, and detected at lower levels in tissues such as lung and exocrine pancreas. {ECO:0000269|PubMed:11302691}.
Protein families:Prohibitin family