PAR11_MOUSE Q8CFF0
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UniProt:Q8CFF0
Recommended name:Protein mono-ADP-ribosyltransferase PARP11
EC number:EC 2.4.2.-
Alternative names:(ADP-ribosyltransferase diphtheria toxin-like 11) (ARTD11) (Poly [ADP-ribose] polymerase 11) (PARP-11)
Cleaved into:
GeneID:101187
Gene names (primary ):Parp11
Gene names (synonym ):
Gene names (ORF ):
Length:331
Mass:38737
Sequence:MFHKTEEFFPKKTDSDVDDMDTSDTQWGWFYLAECGKWHMFQPDTNIQCSVSSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLVTGKQRLIKRAPFSISAFSYICENEAIPMPTHWENVNPDVPYQLVSLQNQTHEYNEVASLFGKTMDRNRIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGVHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH
Tissue specificity:Predominantly expressed in testis, preferentially in postmeiotic germ cells. Also detectable in other tissues, including liver, lung, spleen, thymus and brain. {ECO:0000269|PubMed:25673562}.
Induction:
Developmental stage:Undetectable in testis until postnatal day 18. Sharply up-regulated from postnatal days 18 to 21. This timeframe corresponds to the appearance of the first spermatids of the first wave of spermatogenesis just before initiation of elongation. Remains elevated in adult animals. {ECO:0000269|PubMed:25673562}.
Protein families: