CAPR1_MOUSE   Q60865


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UniProt:Q60865

Recommended name:Caprin-1

EC number:

Alternative names:(Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105)

Cleaved into:

GeneID:53872

Gene names  (primary ):Caprin1

Gene names  (synonym ):Gpiap Gpiap1 Gpip137 M11s1 Rng105

Gene names  (ORF ):G5E5

Length:707

Mass:78169

Sequence:MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDDVRTDLKQGLSGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKALKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPTVEDQVAEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFSSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQSDPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPQVHSESRLAQSNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPMDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPANEPETLKQQSQYQATYNQSFSSQPHQVEQTELQQDQLQTVVGTYHGSQDQPHQVPGNHQQPPQQNTGFPRSSQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYSQSQFTAPRDYSGYQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN

Tissue specificity:Highest expression in thymus, spleen and brain (at protein level). Lower levels in kidney, muscle and liver (at protein level). {ECO:0000269|PubMed:14764709, ECO:0000269|PubMed:20516077}.

Induction:

Developmental stage:Up-regulated when resting T- or B-lymphocytes or hemopoietic progenitors are activated. Down-regulated when a monocytic leukemia cell line, M1, is induced to differentiate. Expressed in brain at 17.5 dpc (at protein level). {ECO:0000269|PubMed:14764709, ECO:0000269|PubMed:20516077}.

Protein families:Caprin family


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