AGRL4_HUMAN Q9HBW9
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UniProt:Q9HBW9
Recommended name：Adhesion G protein-coupled receptor L4
EC number：
Alternative names：(EGF, latrophilin and seven transmembrane domain-containing protein 1) (EGF-TM7-latrophilin-related protein) (ETL protein)
Cleaved into：
GeneID：64123
Gene names (primary )：ADGRL4
Gene names (synonym )：ELTD1 ETL
Gene names (ORF )：UNQ202/PRO228
Length：690
Mass：77811
Sequence：MKRLPLLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVCIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR
Tissue specificity：Detected in the majority of epithelial cells in tumor and normal tissues. Expressed also in human umbilical vein endothelial cells. {ECO:0000269|PubMed:23871637}.
Induction：Up-regulated in tumor endothelial cells. Up-regulated by DLL4. {ECO:0000269|PubMed:23871637}.
Developmental stage：Up-regulated in the adult heart. {ECO:0000269|PubMed:11050079}.
Protein families：G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily