GSDA3_MOUSE   Q5Y4Y6


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UniProt:Q5Y4Y6

Recommended name:Gasdermin-A3

EC number:

Alternative names:(Gasdermin-3)

Cleaved into:Gasdermin-A3, N-terminal (GSDMA3-NT); Gasdermin-A3, C-terminal (GSDMA3-CT)

GeneID:450219

Gene names  (primary ):Gsdma3

Gene names  (synonym ):Gsdm3

Gene names  (ORF ):

Length:464

Mass:52020

Sequence:MPVFEDVTRALVRELNPRGDLTPLDSLIDFKHFRPFCLVLRKRKSTLFWGARYVRTDYTLLDLLEPGSSPSDLTDSGNFSFKNMLDVQVQGLVEVPKTVKVKGTAGLSQSSTLEVQTLSVAPSALENLKKERKLSADHSFLNEMRYHEKNLYVVMEAVEAKQEVTVEQTGNANAIFSLPSLALLGLQGSLNNNKAVTIPKGCVLAYRVRLLRVFLFNLWDIPYICNDSMQTFPKIRRVPCSAFISPTQMISEEPEEEKLIGEMHEDFKTLKEEVQRETQEVEKLSPVGRSSLLTSLSHLLGKKKELQDLEQKLEGALDKGQKVTLEALPKDVLLSKDAMDAILYFLGALTELTEEQLKILVKSLEKKILPVQLKLVESTLEQNFLQDKEGVFPLQPDLLSSLGEEELTLTEALVGLSGLEVQRSGPQYAWDPDTRHNLCALYAGLSLLHLLSRKSNALTYCALS

Tissue specificity:Highest levels in skin with weak expression in placenta and testis. Not detected in the gastrointestinal tract. In skin, expressed in postnatal hair follicles and epidermis as well as sebaceous gland basal cells. {ECO:0000269|PubMed:15475261}.

Induction:

Developmental stage:Not detected at postnatal day 1. Expressed on subsequent postnatal days up to day 20 and throughout adulthood. {ECO:0000269|PubMed:15475261}.

Protein families:Gasdermin family


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