SMAC Rabbit Monoclonal Antibody

SMAC Rabbit Monoclonal Antibody

Cat: AMRe02612
Size:50μL Price:168 $99
Size:100μL Price:300 $180
Application:WB,IHC,ICC/IF,IP
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:DIABLO Category: Recombinant Monoclonal Antibody Tags: , , , , , , , , , ,

Summary

Production Name

SMAC Rabbit Monoclonal Antibody

Description

Recombinant rabbit monoclonal antibody

Host

Rabbit

Application

WB,IHC,ICC/IF,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification

Affinity Purification

 

Immunogen

Gene Name

DIABLO

Alternative Names

SMAC; DFNA64; DIABLO; SMAC3

Gene ID

56616

SwissProt ID

Q9NR28

 

Application

Dilution Ratio

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

Molecular Weight

Calculated MW: 27 kDa; Observed MW: 21 kDa

 

Background

Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.

 

Research Area

Cell Biology

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