CABL1_MOUSE Q9ESJ1
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UniProt:Q9ESJ1
Recommended name:CDK5 and ABL1 enzyme substrate 1
EC number:
Alternative names:(Interactor with CDK3 1) (Ik3-1)
Cleaved into:
GeneID:63955
Gene names (primary ):Cables1
Gene names (synonym ):Cables
Gene names (ORF ):
Length:568
Mass:61429
Sequence:MAAATATAGTAACSSSSSSRGGSTDAAATSGVQPPPPPPATAPPEPLRKPRMDPRRRQAALSFLTNISLDGRPPLQDHEWGGGEEGGGTKPGARARLSLLAAGCNAFSAPGTAAAPWTAGSGSSPCPLPPSLVPRVLGEPSQPPRSAPAVTGAQLQLPDGPGGAGQEELEEDDAFTNVQVPSASFLGSGTPGSTSGSRGRLNSFTQGILPIAFSRQNSQNYCALEQSGQGGSTSALEQLQRSRRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTKNGRDLKLDGGRQSAGAMSLKEIIGLEGVELGADGKTVSYTQFLLPTNAFGNRRNTIDSTASFSQFRSLSHRSLSMGRAGSTQGSLDAGSDLGDFMDYDPNLLDDPQWPCGKHKRVLTFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGFEEPTVAMAFVYFEKLALRGKLNKQNRKLCAGACVLLAAKVGSDLRKHEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLIQSS
Tissue specificity:Ubiquitous. Expressed in postnatal day 1 (P1), in postmitotic neurons of the subplate, cortex (V/VI) and marginal zone; in postnatal day 7 (P7), in all layers of the cerebral cortex and in the CA1 and CA2 regions of the hippocampus (at protein level). Highly expressed in brain, kidney, liver and lung. {ECO:0000269|PubMed:10873625, ECO:0000269|PubMed:10896159}.
Induction:
Developmental stage:Expressed in embryo at 15 dpc and strongly expressed in postmitotic neurons of the subplate, cortical plate, subventrical and marginal zones at 18 dpc (at protein level). Expressed in embryo at 7 dpc onwards. {ECO:0000269|PubMed:10896159}.
Protein families:Cyclin family