LASP1_RAT Q99MZ8
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UniProt:Q99MZ8
Recommended name：LIM and SH3 domain protein 1
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GeneID：29278
Gene names (primary )：Lasp1
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Length：263
Mass：29,970
Sequence：MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGIEPERREAQDSSSYRRPTEQQQPQPHHIPTSAPVYQQPQQQQVTPSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI
Tissue specificity：Expressed in a wide range of tissues (but not the heart or skeletal muscle), the expression is specific for certain actin-rich cell types within these tissues. Expression is prominent in the cortical regions of ion-transporting duct cells in the pancreas, in the salivary parotid gland and in certain F-actin-rich cells in the distal tubule/collecting duct. In primary cultures of gastric fibroblasts, expression is mainly within the tips of lamellipodia and at the leading edges of membrane ruffles. 1
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