TIGIT_HUMAN   Q495A1


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UniProt:Q495A1

Recommended name:T-cell immunoreceptor with Ig and ITIM domains

EC number:

Alternative names:(V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3)

Cleaved into:

GeneID:201633

Gene names  (primary ):TIGIT

Gene names  (synonym ):VSIG9 VSTM3

Gene names  (ORF ):

Length:244

Mass:26319

Sequence:MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLRRKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFFTETG

Tissue specificity:Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). {ECO:0000269|PubMed:19011627}.

Induction:

Developmental stage:

Protein families:


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