PSN2_HUMAN P49810
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UniProt:P49810
Recommended name：Presenilin-2
EC number：EC:3.4.23.-
Alternative names：(PS-2) (AD3LP) (AD5) (E5-1) (STM-2)
Cleaved into：Presenilin-2 NTF subunit; Presenilin-2 CTF subunit
GeneID：5664
Gene names (primary )：PSEN2
Gene names (synonym )：AD4 PS2 PSNL2 STM2
Gene names (ORF )：
Length：448
Mass：50140
Sequence：MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
Tissue specificity：Isoform 1 is seen in the placenta, skeletal muscle and heart while isoform 2 is seen in the heart, brain, placenta, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:8574969}.
Induction：
Developmental stage：
Protein families：Peptidase A22A family