NR1H3_HUMAN   Q13133


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UniProt:Q13133

Recommended name:Oxysterols receptor LXR-alpha

EC number:

Alternative names:(Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3)

Cleaved into:

GeneID:10062

Gene names  (primary ):NR1H3

Gene names  (synonym ):LXRA

Gene names  (ORF ):

Length:447

Mass:50396

Sequence:MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Tissue specificity:Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.

Induction:By 9-cis retinoic acid (9CRA).

Developmental stage:

Protein families:Nuclear hormone receptor family, NR1 subfamily


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