NR1H3_HUMAN Q13133
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UniProt:Q13133
Recommended name:Oxysterols receptor LXR-alpha
EC number:
Alternative names:(Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3)
Cleaved into:
GeneID:10062
Gene names (primary ):NR1H3
Gene names (synonym ):LXRA
Gene names (ORF ):
Length:447
Mass:50396
Sequence:MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Tissue specificity:Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
Induction:By 9-cis retinoic acid (9CRA).
Developmental stage:
Protein families:Nuclear hormone receptor family, NR1 subfamily