MK_HUMAN P21741
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UniProt:P21741
Recommended name:Midkine
EC number:
Alternative names:(MK) (Amphiregulin-associated protein) (ARAP) (Midgestation and kidney protein) (Neurite outgrowth-promoting factor 2) (Neurite outgrowth-promoting protein)
Cleaved into:
GeneID:4192
Gene names (primary ):MDK
Gene names (synonym ):MK1 NEGF2
Gene names (ORF ):
Length:143
Mass:15585
Sequence:MQHRGFLLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGTCGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETIRVTKPCTPKTKAKAKAKKGKGKD
Tissue specificity:Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions. {ECO:0000269|PubMed:17379400}.
Induction:By heparin and retinoic acid. {ECO:0000269|PubMed:1768439, ECO:0000269|PubMed:8241100}.
Developmental stage:
Protein families:Pleiotrophin family