PHLA3_HUMAN Q9Y5J5
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UniProt:Q9Y5J5
Recommended name:Pleckstrin homology-like domain family A member 3
EC number:
Alternative names:(TDAG51/Ipl homolog 1)
Cleaved into:
GeneID:23612
Gene names (primary ):PHLDA3
Gene names (synonym ):TIH1
Gene names (ORF ):
Length:127
Mass:13891
Sequence:MTAAATATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSLGTGTLVS
Tissue specificity:Widely expressed with lowest expression in liver and spleen. {ECO:0000269|PubMed:10594239}.
Induction:By p53/TP53; expression is directly activated by TP53. TP53 phosphorylation on 'Ser-15' is required to activate the PHLDA3 promoter. {ECO:0000269|PubMed:15940259, ECO:0000269|PubMed:19203586}.
Developmental stage:
Protein families:PHLDA3 family