PHLA3_HUMAN   Q9Y5J5


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UniProt:Q9Y5J5

Recommended name:Pleckstrin homology-like domain family A member 3

EC number:

Alternative names:(TDAG51/Ipl homolog 1)

Cleaved into:

GeneID:23612

Gene names  (primary ):PHLDA3

Gene names  (synonym ):TIH1

Gene names  (ORF ):

Length:127

Mass:13891

Sequence:MTAAATATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSLGTGTLVS

Tissue specificity:Widely expressed with lowest expression in liver and spleen. {ECO:0000269|PubMed:10594239}.

Induction:By p53/TP53; expression is directly activated by TP53. TP53 phosphorylation on 'Ser-15' is required to activate the PHLDA3 promoter. {ECO:0000269|PubMed:15940259, ECO:0000269|PubMed:19203586}.

Developmental stage:

Protein families:PHLDA3 family


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