PRD11_HUMAN Q9NQV5
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UniProt:Q9NQV5
Recommended name：PR domain-containing protein 11
EC number：EC:2.1.1.-
Alternative names：
Cleaved into：
GeneID：56981
Gene names (primary )：PRDM11
Gene names (synonym )：PFM8
Gene names (ORF )：
Length：511
Mass：57863
Sequence：MLKMAEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKADSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELPEFSDPAGKLVWMRLLSEGRVRSGLCGG
Tissue specificity：Highly expressed in lung, including bronchial epithelial cells and airway smooth muscle cells, as well as in peripheral blood mononuclear cells. In tonsils, expressed in B-cell types, including naive B-cells, centroblasts, centrocytes and memory B-cells (at protein level). In benign hyperplastic lymph nodes, expressed in germinal center cells in both the dark and light zones, as well as in scattered cells in the mantle zone and the interfollicular area (at protein level). {ECO:0000269|PubMed:24929828, ECO:0000269|PubMed:25499759}.
Induction：
Developmental stage：Differential expressed during pseudoglandular and canalicular stages of lung development. {ECO:0000269|PubMed:24929828}.
Protein families：Class V-like SAM-binding methyltransferase superfamily