AR6P1_HUMAN Q15041
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UniProt:Q15041
Recommended name:ADP-ribosylation factor-like protein 6-interacting protein 1
EC number:
Alternative names:(ARL-6-interacting protein 1) (Aip-1) (Apoptotic regulator in the membrane of the endoplasmic reticulum)
Cleaved into:
GeneID:23204
Gene names (primary ):ARL6IP1
Gene names (synonym ):ARL6IP ARMER KIAA0069
Gene names (ORF ):
Length:203
Mass:23363
Sequence:MAEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLIIYYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIVSLAAVAWVGQQVHNLLLTYLIVTSLLLLPGLNQHGIILKYIGMAKREINKLLKQKEKKNE
Tissue specificity:Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart. {ECO:0000269|PubMed:10995579}.
Induction:Down-regulated by apoptotic stimuli. {ECO:0000269|PubMed:12754298}.
Developmental stage:Down-regulated during myeloid differentiation.
Protein families:ARL6ip family