AR6P1_HUMAN   Q15041


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UniProt:Q15041

Recommended name:ADP-ribosylation factor-like protein 6-interacting protein 1

EC number:

Alternative names:(ARL-6-interacting protein 1) (Aip-1) (Apoptotic regulator in the membrane of the endoplasmic reticulum)

Cleaved into:

GeneID:23204

Gene names  (primary ):ARL6IP1

Gene names  (synonym ):ARL6IP ARMER KIAA0069

Gene names  (ORF ):

Length:203

Mass:23363

Sequence:MAEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLIIYYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIVSLAAVAWVGQQVHNLLLTYLIVTSLLLLPGLNQHGIILKYIGMAKREINKLLKQKEKKNE

Tissue specificity:Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart. {ECO:0000269|PubMed:10995579}.

Induction:Down-regulated by apoptotic stimuli. {ECO:0000269|PubMed:12754298}.

Developmental stage:Down-regulated during myeloid differentiation.

Protein families:ARL6ip family


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