PERF_MOUSE P10820
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UniProt:P10820
Recommended name:Perforin-1
EC number:
Alternative names:(P1) (Cytolysin) (Lymphocyte pore-forming protein)
Cleaved into:
GeneID:18646
Gene names (primary ):Prf1
Gene names (synonym ):Pfp
Gene names (ORF ):
Length:554
Mass:62081
Sequence:MATCLFLLGLFLLLPRPVPAPCYTATRSECKQKHKFVPGVWMAGEGMDVTTLRRSGSFPVNTQRFLRPDRTCTLCKNSLMRDATQRLPVAITHWRPHSSHCQRNVAAAKVHSTEGVAREAAANINNDWRVGLDVNPRPEANMRASVAGSHSKVANFAAEKTYQDQYNFNSDTVECRMYSFRLVQKPPLHLDFKKALRALPRNFNSSTEHAYHRLISSYGTHFITAVDLGGRISVLTALRTCQLTLNGLTADEVGDCLNVEAQVSIGAQASVSSEYKACEEKKKQHKMATSFHQTYRERHVEVLGGPLDSTHDLLFGNQATPEQFSTWTASLPSNPGLVDYSLEPLHTLLEEQNPKREALRQAISHYIMSRARWQNCSRPCRSGQHKSSHDSCQCECQDSKVTNQDCCPRQRGLAHLVVSNFRAEHLWGDYTTATDAYLKVFFGGQEFRTGVVWNNNNPRWTDKMDFENVLLSTGGPLRVQVWDADYGWDDDLLGSCDRSPHSGFHEVTCELNHGRVKFSYHAKCLPHLTGGTCLEYAPQGLLGDPPGNRSGAVW
Tissue specificity:Detected in cytotoxic T-lymphocytes and natural killer cells. {ECO:0000269|PubMed:2040805, ECO:0000269|PubMed:2783486, ECO:0000269|PubMed:3261391}.
Induction:
Developmental stage:
Protein families:Complement C6/C7/C8/C9 family