NEK2_MOUSE O35942
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UniProt:O35942
Recommended name：Serine/threonine-protein kinase Nek2
EC number：EC 2.7.11.1
Alternative names：(Never in mitosis A-related kinase 2) (NimA-related protein kinase 2)
Cleaved into：
GeneID：18005
Gene names (primary )：Nek2
Gene names (synonym )：
Gene names (ORF )：
Length：443
Mass：51243
Sequence：MPSRVEDYEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEVEKQMLVSEVNLLRELKHPNIVSYYDRIIDRTNTTLYIVMEYCEGGDLASVISKGTKDRQYLEEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDSKHNVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMSCLSYNEKSDIWSLGCLLYELCALMPPFTAFNQKELAGKIREGRFRRIPYRYSDGLNDLITRMLNLKDYHRPSVEEILESPLIADLVAEEQRRNLERRGRRSGEPSKLPDSSPVLSELKLKERQLQDREQALRAREDILEQKERELCIRERLAEDKLARAESLMKNYSLLKEHRLLCLAGGPELDLPSSAMKKKVHFHGESKENTARSENSESYLAKSKCRDLKKRLHAAQLRAQALADIEKNYQLKSRQILGMR
Tissue specificity：Most abundantly expressed in testis. Low levels found in mid-gestation embryo, ovary, placenta, intestine, thymus and skin. Within the testis, expression restricted to germ cells with highest levels detected in spermatocytes at pachytene and diplotene stages. Also expressed in meiotic pachytene oocytes. {ECO:0000269|PubMed:9187143, ECO:0000269|PubMed:9434622}.
Induction：
Developmental stage：
Protein families：Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily