MP2K2_MOUSE Q63932
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UniProt:Q63932
Recommended name:Dual specificity mitogen-activated protein kinase kinase 2
EC number:EC 2.7.12.2
Alternative names:(MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Cleaved into:
GeneID:26396
Gene names (primary ):Map2k2
Gene names (synonym ):Mek2 Mkk2 Prkmk2
Gene names (ORF ):
Length:401
Mass:44402
Sequence:MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLMNHAFIKRSEGEEVDFAGWLCRTLRLKQPSTPTRTAV
Tissue specificity:Expressed in adult intestine, kidney, liver, lung, pancreas, spleen, thymus, and at high levels in the neonatal brain. Lower expression is found in adult brain and heart.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily