MP2K2_MOUSE   Q63932


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UniProt:Q63932

Recommended name:Dual specificity mitogen-activated protein kinase kinase 2

EC number:EC 2.7.12.2

Alternative names:(MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)

Cleaved into:

GeneID:26396

Gene names  (primary ):Map2k2

Gene names  (synonym ):Mek2 Mkk2 Prkmk2

Gene names  (ORF ):

Length:401

Mass:44402

Sequence:MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLMNHAFIKRSEGEEVDFAGWLCRTLRLKQPSTPTRTAV

Tissue specificity:Expressed in adult intestine, kidney, liver, lung, pancreas, spleen, thymus, and at high levels in the neonatal brain. Lower expression is found in adult brain and heart.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily


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