MK12_MOUSE O08911
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UniProt:O08911
Recommended name:Mitogen-activated protein kinase 12
EC number:EC 2.7.11.24
Alternative names:(MAP kinase 12) (MAPK 12) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)
Cleaved into:
GeneID:29857
Gene names (primary ):Mapk12
Gene names (synonym ):Sapk3
Gene names (ORF ):
Length:367
Mass:42043
Sequence:MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTAAEALTHPYFESLRDTEDEPKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRQLGARVPKETAL
Tissue specificity:Highly expressed in skeletal muscle. Also expressed in the heart, particularly in cardiac myocytes, lung, thymus and testes. {ECO:0000269|PubMed:11991731}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily