KRT36_MOUSE B1AQ75
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UniProt:B1AQ75
Recommended name:Keratin, type I cuticular Ha6
EC number:
Alternative names:(Keratin-36) (K36) (Keratin-5) (MHRa-1) (Type I keratin 48 kDa)
Cleaved into:
GeneID:16673
Gene names (primary ):Krt36
Gene names (synonym ):Hra-1 Krt1-22 Krt1-5
Gene names (ORF ):
Length:473
Mass:52790
Sequence:MATQICTPTFSAGSAKGLCGTSGSFSRISSIHSMGSCRAPSLVGTVGSVSSFRTGFSGPGSCLPGSYLSSGCHSSGFAGSGGWFCEGAFNGNEKATMQILNDRLANYLEKVRQLEQENTQLECRIREWYECQIPYICPDYQSYFKTAEELQQKILLTKSENARLILQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELLCLKRNHEEEVNALRSQLGDRLNVEVDAAPPVDLNKILDDMRCQYETLVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNSLEIELQAQQSMRNSLESTLAETEARYSSQLGQMQCLITNVESQLAEIRCDLERQNHEYQVLLDVKARLESEIATYRRLLDGEDCKLPAHPCSTECKPAVRVPYIPSTTCTPAGPCTPAGPCTPAPQVSTQIRTITEEIRDGRVISSREHVVPRAM
Tissue specificity:In skin, only expressed in the suprabasal cells of tail scale epidermis. Suprabasally expressed in stratified squamous epithelia and also in the posterior unit of the complex filiform papillae of tongue. Expressed in rare anatomical sites in which an orthokeratinized stratum corneum would be too soft and a hard keratinized structure would be too rigid to meet the functional requirement of the respective epithelia. {ECO:0000269|PubMed:1385239}.
Induction:mRNA synthesis is suppressed during retinoic acid-mediated orthokeratotic conversion of tail scale epidermis. {ECO:0000269|PubMed:1385239}.
Developmental stage:
Protein families:Intermediate filament family