PLK3_MOUSE   Q60806


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UniProt:Q60806

Recommended name:Serine/threonine-protein kinase PLK3

EC number:EC 2.7.11.21

Alternative names:(Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3)

Cleaved into:

GeneID:

Gene names  (primary ):Plk3

Gene names  (synonym ):Cnk Fnk

Gene names  (ORF ):

Length:631

Mass:70012

Sequence:MEPAAGFLSPRPFPRAAVPSAPPAGPGPPANASPRSEPEVLAGPRAPDPPGRLITDPLSGRTYTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTKGYTPDRLPVSSCVTVPDLTPPNPARSLFAKVTKSLFGRKKNKNKNHSEDQDNVSCLAPVVSGQAPASLIETAAEDSSPRGTLASSGDGFEEGLTVATVVESALCALRNCVAFMPPAEQNPAPLAQPEPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSMGSVPRALQPQLGILRYFASYMEQHLMKGGDLPSVEEAEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLLVTFVARNRSACTYLASHLRQLGCSPDLRQRLRYALRLLRDQSPA

Tissue specificity:Expressed in skin.

Induction:Negatively regulated by TTP family members: TTP binds to the 3'-untranslated region (3'-UTR) of PLK3 mRNAs, contributing to the rapid degradation of transcripts. {ECO:0000269|PubMed:19188452}.

Developmental stage:

Protein families:Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily


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