PLK3_MOUSE Q60806
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UniProt:Q60806
Recommended name:Serine/threonine-protein kinase PLK3
EC number:EC 2.7.11.21
Alternative names:(Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3)
Cleaved into:
GeneID:
Gene names (primary ):Plk3
Gene names (synonym ):Cnk Fnk
Gene names (ORF ):
Length:631
Mass:70012
Sequence:MEPAAGFLSPRPFPRAAVPSAPPAGPGPPANASPRSEPEVLAGPRAPDPPGRLITDPLSGRTYTKGRLLGKGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTKGYTPDRLPVSSCVTVPDLTPPNPARSLFAKVTKSLFGRKKNKNKNHSEDQDNVSCLAPVVSGQAPASLIETAAEDSSPRGTLASSGDGFEEGLTVATVVESALCALRNCVAFMPPAEQNPAPLAQPEPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSMGSVPRALQPQLGILRYFASYMEQHLMKGGDLPSVEEAEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLLVTFVARNRSACTYLASHLRQLGCSPDLRQRLRYALRLLRDQSPA
Tissue specificity:Expressed in skin.
Induction:Negatively regulated by TTP family members: TTP binds to the 3'-untranslated region (3'-UTR) of PLK3 mRNAs, contributing to the rapid degradation of transcripts. {ECO:0000269|PubMed:19188452}.
Developmental stage:
Protein families:Protein kinase superfamily, Ser/Thr protein kinase family, CDC5/Polo subfamily