CP7A1_MOUSE Q64505
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UniProt:Q64505
Recommended name:Cytochrome P450 7A1
EC number:EC 1.14.14.26
Alternative names:(24-hydroxycholesterol 7-alpha-hydroxylase) (CYPVII) (Cholesterol 7-alpha-hydroxylase) (Cholesterol 7-alpha-monooxygenase) (EC 1.14.14.23)
Cleaved into:
GeneID:13122
Gene names (primary ):Cyp7a1
Gene names (synonym ):Cyp7
Gene names (ORF ):
Length:503
Mass:57262
Sequence:MMSISLIWGIAVVVSCCIWFIIGIRRRKVGEPPLDNGLIPYLGCALKFGSNPLEFLRAKQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPSDGNTTENINKTFNKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSAVWVTEGMYAFCYRVMFEAGYLTLFGKDISKTDSQRAFIQNNLDSFKQFDQVFPALVAGVPIHLFKTAHKARERLAESLKHKNLYMRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLVILWASQANTIPATFWSLFQMIRSPEAMKAASEEVNGALQSAGQELSSGGNAIYLDQEQLNNLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYRNGNKLKYFYMPFGSGATICPGRLFAVQEIKQFLILMLSYFELELVESHTKCPPLDQSRAGLGILPPLNDIEFKYKLKH
Tissue specificity:
Induction:Up-regulated by fasting, returns to ground state upon feeding. Up-regulated by experimentally induced diabetes. Down-regulated by insulin treatment. {ECO:0000269|PubMed:14522988, ECO:0000269|PubMed:17636037}.
Developmental stage:
Protein families:Cytochrome P450 family