U17PA_MOUSE Q61068
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UniProt:Q61068
Recommended name:Ubiquitin carboxyl-terminal hydrolase 17-like protein A
EC number:EC 3.4.19.12
Alternative names:(USP17-A) (Deubiquitinating enzyme 1) (Ubiquitin carboxyl-terminal hydrolase DUB-1) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1)
Cleaved into:
GeneID:13531
Gene names (primary ):Usp17la
Gene names (synonym ):Dub-1 Dub1
Gene names (ORF ):
Length:526
Mass:59073
Sequence:MVVALSFPEADPALSSPDAPELHQDEAQVVEELTVNGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKLCAMEALVTQSLLHSHSGDVMKPSHILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSKPTSEDSSPIHDIFGGWWRSQIKCLLCQGTSDTYDRFLDIPLDISSAQSVKQALWDTEKSEELCGDNAYYCGKCRQKMPASKTLHVHIAPKVLMVVLNRFSAFTGNKLDRKVSYPEFLDLKPYLSEPTGGPLPYALYAVLVHDGATSHSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQANLKQVSIDMPEGRINEVLDPEYQLKKSRRKKHKKKSPFTEDLGEPCENRDKRAIKETSLGKGKVLQEVNHKKAGQKHGNTKLMPQKQNHQKAGQNLRNTEVELDLPADAIVIHQPRSTANWGRDSPDKENQPLHNADRLLTSQGPVNTWQLCRQEGRRRSKKGQNKNKQGQRLLLVC
Tissue specificity:Expressed in hematopoietic progenitor cell lines Ba/F3 and FDCP1. Not detected in brain, lung, liver, kidney, thymus, spleen and bone marrow. {ECO:0000269|PubMed:8756639}.
Induction:Up-regulated by IL3, IL5 and CSF2. {ECO:0000269|PubMed:8622927, ECO:0000269|PubMed:8756639}.
Developmental stage:
Protein families:Peptidase C19 family