E41L5_MOUSE   Q8BGS1


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UniProt:Q8BGS1

Recommended name:Band 4.1-like protein 5

EC number:

Alternative names:(Erythrocyte membrane protein band 4.1-like 5)

Cleaved into:

GeneID:226352

Gene names  (primary ):Epb41l5

Gene names  (synonym ):Epb4.1l5 Kiaa1548

Gene names  (ORF ):

Length:731

Mass:81636

Sequence:MLSFLRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDAKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKASTTQPEDLGVLNASAQKSDSQQAWGVMSPVPVTSSSSCGAVQVEIENLPQTSATEQHDRKCLPLSVDLLNSPDLLETTIGDVTRTSETSAPFPAPDTINVATRSNELEEFKAECETLKDDTEKLKQLETEQTILPSLRPTIDINVNSQEEVVKLTEKCLNNAIENPALNAVKVPPDFKSNILKAQVEAVHKVTREDSLLTHKNASVQDAATNSTAFNENDVPVCKDSLTPVHGTAADSASVLKDATDELDALLLSLTENLMDHTVTPQVSSPSMITPRWIIPQSATISNGLAGYGASLAGTDECSQKDGFSLISPPAPFLVDAVTSSAPPLPEDSTLKQKCLLTTEL

Tissue specificity:In the retina, expressed at the outer limiting membrane, retinal pigment epithelium, outer nuclear layer and outer plexiform layer (at protein level) (PubMed:17920587). Also detected in the inner segments (at protein level) (PubMed:17920587). Expressed at the basolateral and apical sides of the mesonephric tubules in the kidney (at protein level) (PubMed:17920587). {ECO:0000269|PubMed:17920587}.

Induction:

Developmental stage:At 10.5 dpc, strongly expressed in the developing neural tube and optic vesicle, as well as in the branchial arches and kidney (PubMed:17920587). In the developing kidney, detected in the mesonephrotic tubules (PubMed:17920587). At 11.5 dpc, expressed along the entire cranial-caudal length of the developing neural tube, including the anterior forebrain and the posterior spinal cord (PubMed:17920587). Always restricted to the ventricular layer, where proliferative cells are located (PubMed:17920587). Conversely, not detected in postmitotic neural compartments (PubMed:17920587). In the developing lung, at 11.5 dpc, expressed in the internal endodermal layer and in particular in the nascent bronchial tips (PubMed:17920587). At 12.5 dpc, expressed in the optic vesicle, detected mainly in the retinal layer (PubMed:17920587). The retinal pigment epithelium shows only background levels (PubMed:17920587). At 15.5 dpc expressed at the basolateral side of the plasma membrane in brain, spinal cord, kidney, testis, intestine, skin, and muscles (PubMed:17920587). {ECO:0000269|PubMed:17920587}.

Protein families:


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