ASB4_MOUSE Q9WV71
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UniProt:Q9WV71
Recommended name：Ankyrin repeat and SOCS box protein 4
EC number：
Alternative names：(ASB-4)
Cleaved into：
GeneID：65255
Gene names (primary )：Asb4
Gene names (synonym )：
Gene names (ORF )：
Length：426
Mass：48098
Sequence：MDGITAPISKAGAAKLVKKDFLEALKTNDFGKLKAILIERQIDVDTVFEVEDENMILASYKQGYWLPSYKLKSSWATGLHLSVLLGHVECLMVLLDHNATINCRPNGKTPLHVACEIANLECVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVLRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVENGAIVDSMNAHMETPLAIATYWALRFKEQEYSREHHLICRTLLDNNAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHSCPKAIEVVVNAYEHIRWNIKWRRAIPDDDLEKHWDFYHSLFKVCCNTPRTLMHLSRCAIRKALHNRCHKAIPMLSLPLPLKKYLLLEPEGIIY
Tissue specificity：Highest expression detected in testis, with some expression detected in ovary and heart. Not detected in lung, kidney, liver, spleen and bone marrow. {ECO:0000269|PubMed:11111040, ECO:0000269|PubMed:17636018}.
Induction：
Developmental stage：Differentially expressed in the vascular lineage during embryonic stem (ES) cell differentiation, with expression increasing when the cells differentiate. At 7.5 dpc, no remarkable expression is detected. At 9.5 dpc, expressed in intersomitic vessels, dorsal aorta, forelimb buds, allantois/umbilical vessels, vitelline vessels, septum transversum, proepicardium, capillary plexi of the head and branchial arches, endocardium, yolk sac vasculature and placenta. At 10.5 dpc, expressed in forelimb and hind limb buds, intersomitic vessels, peripheral liver cells and umbilical vessels, with expression in the capillary plexi of the head and branchial arches no longer detected. At 11.5 dpc, high expression levels are limited to forelimbs and hind limbs and the most caudal intersomitic vessels. {ECO:0000269|PubMed:17636018}.
Protein families：Ankyrin SOCS box (ASB) family