CASPE_MOUSE   O89094


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UniProt:O89094

Recommended name:Caspase-14

EC number:EC 3.4.22.-

Alternative names:(CASP-14) (Mini-ICE) (MICE)

Cleaved into:Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form

GeneID:12365

Gene names  (primary ):Casp14

Gene names  (synonym ):

Gene names  (ORF ):

Length:257

Mass:29458

Sequence:MESEMSDPQPLQEERYDMSGARLALTLCVTKAREGSEVDMEALERMFRYLKFESTMKRDPTAQQFLEELDEFQQTIDNWEEPVSCAFVVLMAHGEEGLLKGEDEKMVRLEDLFEVLNNKNCKALRGKPKVYIIQACRGEHRDPGEELRGNEELGGDEELGGDEVAVLKNNPQSIPTYTDTLHIYSTVEGYLSYRHDEKGSGFIQTLTDVFIHKKGSILELTEEITRLMANTEVMQEGKPRKVNPEVQSTLRKKLYLQ

Tissue specificity:Embryo, adult liver and less in adult brain and kidney. Expressed in differentiating keratinocytes of embryonic skin (at protein level). Expressed in keratinocytes of adult skin suprabasal layers (at protein level). {ECO:0000269|PubMed:10203698, ECO:0000269|PubMed:11175259}.

Induction:

Developmental stage:Expressed at embryonic day 18 specifically in cornified epithelium in the suprabasal layers. {ECO:0000269|PubMed:11526440}.

Protein families:Peptidase C14A family


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