CASPE_MOUSE O89094
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UniProt:O89094
Recommended name:Caspase-14
EC number:EC 3.4.22.-
Alternative names:(CASP-14) (Mini-ICE) (MICE)
Cleaved into:Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form
GeneID:12365
Gene names (primary ):Casp14
Gene names (synonym ):
Gene names (ORF ):
Length:257
Mass:29458
Sequence:MESEMSDPQPLQEERYDMSGARLALTLCVTKAREGSEVDMEALERMFRYLKFESTMKRDPTAQQFLEELDEFQQTIDNWEEPVSCAFVVLMAHGEEGLLKGEDEKMVRLEDLFEVLNNKNCKALRGKPKVYIIQACRGEHRDPGEELRGNEELGGDEELGGDEVAVLKNNPQSIPTYTDTLHIYSTVEGYLSYRHDEKGSGFIQTLTDVFIHKKGSILELTEEITRLMANTEVMQEGKPRKVNPEVQSTLRKKLYLQ
Tissue specificity:Embryo, adult liver and less in adult brain and kidney. Expressed in differentiating keratinocytes of embryonic skin (at protein level). Expressed in keratinocytes of adult skin suprabasal layers (at protein level). {ECO:0000269|PubMed:10203698, ECO:0000269|PubMed:11175259}.
Induction:
Developmental stage:Expressed at embryonic day 18 specifically in cornified epithelium in the suprabasal layers. {ECO:0000269|PubMed:11526440}.
Protein families:Peptidase C14A family