FUT9_MOUSE O88819
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UniProt:O88819
Recommended name:4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9
EC number:EC 2.4.1.152
Alternative names:(Fucosyltransferase 9) (Fucosyltransferase IX) (Fuc-TIX) (FucT-IX) (Galactoside 3-L-fucosyltransferase)
Cleaved into:
GeneID:14348
Gene names (primary ):Fut9
Gene names (synonym ):
Gene names (ORF ):
Length:359
Mass:42041
Sequence:MTSTSKGILRPFLIVCIILGCFMACLLIYIKPTNSWVFSPMESASSVLKMKNFFSTKTDYFNETTILVWVWPFGQTFDLTSCQAMFNIQGCHLTTDRSLYNKSHAVLIHHRDISWDLTNLPQQARPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFLTVSTNPFVFEVPSKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQAFGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSRENYENYIPADSFIHVEDFNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN
Tissue specificity:Mainly detected in brain and kidney. {ECO:0000269|PubMed:9756916}.
Induction:
Developmental stage:Expressed in 1-cell embryos and then decreased dramatically in 2- and 4-cell embryos. It increases transiently in 8-cell embryos and then vanishes completely at the morula stage (PubMed:15121843). Predominantly expressed at all stages both in cerebrum and in cerebellum containing mesencephalon. Expression increases during the embryonic stage with the highest expression at P0 and decreases. Expression increases from the embryo to P7 stage, with the highest expression at P7, and decreases in adult brain. At P7 expressed in the neurons in layers II-IV and those in layers V and VI of the cerebral cortex. At P7 expressed in cerebellum, granule neurons in the internal granule cell layer (PubMed:12626397). {ECO:0000269|PubMed:12626397, ECO:0000269|PubMed:15121843}.
Protein families:Glycosyltransferase 10 family