PRS29_MOUSE   Q99MS4


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UniProt:Q99MS4

Recommended name:Serine protease 29

EC number:EC 3.4.21.-

Alternative names:(Implantation serine proteinase 2) (ISP-2) (Strypsin-2) (Strypsin-related protein) (Tryptase-like proteinase)

Cleaved into:

GeneID:114662

Gene names  (primary ):Prss29

Gene names  (synonym ):Isp2

Gene names  (ORF ):

Length:279

Mass:30986

Sequence:MLIQLCLTLFFLGCSIAGTPAPGPEDVLMGIVGGHSAPQGKWPWQVSLRIYRYYWAFWVHNCGGSIIHPQWVLTAAHCIRERDADPSVFRIRVGEAYLYGGKELLSVSRVIIHPDFVHAGLGSDVALLQLAVSVQSFPNVKPVKLPSESLEVTKKDVCWVTGWGAVSTHRSLPPPYRLQQVQVKIIDNSLCEEMYHNATRHRNRGQKLILKDMLCAGNQGQDSCYGDSGGPLVCNVTGSWTLVGVVSWGYGCALRDFPGVYARVQSFLPWITQQMQRFS

Tissue specificity:Expressed in embryos and placenta. Found in uterus especially in glandular epithelium during zona lysis and implantation. {ECO:0000269|PubMed:11467974, ECO:0000269|PubMed:12112596}.

Induction:Up-regulated in uterine endometrial glands following the initiation of embryo implantation. By progesterone. {ECO:0000269|PubMed:11467974, ECO:0000269|PubMed:15304212, ECO:0000269|PubMed:15349836}.

Developmental stage:Highly expressed from 6.5 dpc plus deciduum. Also expressed, but to a lower extent, in placenta from 11.5 dpc and 13.5 dpc. Not expressed at 8.5 dpc and 11.5 dpc in embryo proper. Expressed at 4.0 dpc in uterus. {ECO:0000269|PubMed:11467974, ECO:0000269|PubMed:12883636, ECO:0000269|PubMed:15349836}.

Protein families:Peptidase S1 family


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