PRDM6_MOUSE Q3UZD5
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UniProt:Q3UZD5
Recommended name：Putative histone-lysine N-methyltransferase PRDM6
EC number：EC 2.1.1.361
Alternative names：(PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle)
Cleaved into：
GeneID：225518
Gene names (primary )：Prdm6
Gene names (synonym )：Gm92 Prism
Gene names (ORF )：
Length：596
Mass：64503
Sequence：MLKPGDPGGSAFLKVDPAYLQHWQQLFPHGGGGGGPLKASGAALALGAPQPLQPPPPPPPPPPERAEPPPDGLRPRPASLSSTPAPSSTSASSASSCAAAAAAAALAGLSALPVAQMPVFAPLAAAAVAAEPLPPKDLCLGASAGPGPAKCGGGGGSVGDGRGVPRFRCSAEELDYYLYGQQRMEIIPLNQHTSDPNNRCDMCADNRNGECPMHGPLHSLRRLVGTSSAAAAAPPPELPEWLRDLPREVCLCTSTVPGLAYGICAAQRIQQGTWIGPFQGVLLSPEKVQTGVVRNTQHLWEIYDQDGTLQHFIDGGEPSKSSWMRYIRCARHCGEQNLTVVQYRSNIFYRACIDIPRGTELLVWYNDSYTSFFGIPLQCIAQDENLNVPSTVMEAMCRQDALQPFNKSSKLSPSGQQRSVVFPQTPCSRNFSLLDKSGPMEAGFNQINVKNQRVLASPTSTSQLHSEFSDWHLWKCGQCFKTFTQRILLQMHVCTQNPDRPYQCGHCSQSFSQPSELRNHVVTHSSDRPFKCGYCGRAFAGATTLNNHIRTHTGEKPFKCERCERSFTQATQLSRHQRMPNECKPITESPESIEVD
Tissue specificity：Expressed in a variety of smooth muscle-containing tissues and displays especially robust expression in the cardiac outflow tract and descending aorta during embryogenesis. Also enriched in vascular precursors during development. {ECO:0000269|PubMed:16537907, ECO:0000269|PubMed:17662997, ECO:0000269|PubMed:27181681}.
Induction：
Developmental stage：Highly expressed in ductus arteriosus prenatally, expression declines rapildy after birth. {ECO:0000269|PubMed:27181681}.
Protein families：Class V-like SAM-binding methyltransferase superfamily