HPSE_MOUSE Q6YGZ1
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UniProt:Q6YGZ1
Recommended name：Heparanase
EC number：EC 3.2.1.166
Alternative names：(Endo-glucoronidase)
Cleaved into：Heparanase 8 kDa subunit; Heparanase 50 kDa subunit
GeneID：15442
Gene names (primary )：Hpse
Gene names (synonym )：Hpa
Gene names (ORF )：
Length：535
Mass：60066
Sequence：MLRLLLLWLWGPLGALAQGAPAGTAPTDDVVDLEFYTKRPLRSVSPSFLSITIDASLATDPRFLTFLGSPRLRALARGLSPAYLRFGGTKTDFLIFDPDKEPTSEERSYWKSQVNHDICRSEPVSAAVLRKLQVEWPFQELLLLREQYQKEFKNSTYSRSSVDMLYSFAKCSGLDLIFGLNALLRTPDLRWNSSNAQLLLDYCSSKGYNISWELGNEPNSFWKKAHILIDGLQLGEDFVELHKLLQRSAFQNAKLYGPDIGQPRGKTVKLLRSFLKAGGEVIDSLTWHHYYLNGRIATKEDFLSSDVLDTFILSVQKILKVTKEITPGKKVWLGETSSAYGGGAPLLSNTFAAGFMWLDKLGLSAQMGIEVVMRQVFFGAGNYHLVDENFEPLPDYWLSLLFKKLVGPRVLLSRVKGPDRSKLRVYLHCTNVYHPRYQEGDLTLYVLNLHNVTKHLKVPPPLFRKPVDTYLLKPSGPDGLLSKSVQLNGQILKMVDEQTLPALTEKPLPAGSALSLPAFSYGFFVIRNAKIAACI
Tissue specificity：Expressed in skin, mainly in the stratum granulosum and the first layer of the stratum corneum in the upper part of the epidermis. Also detected in hair follicles and in sebaceous glands. {ECO:0000269|PubMed:15793281, ECO:0000269|PubMed:18589009}.
Induction：
Developmental stage：In 18.5 day embryos, expressed in the peri-chondrium, periosteum and at the chondro-osseus junction of developing bone. {ECO:0000269|PubMed:15677344}.
Protein families：Glycosyl hydrolase 79 family