Cytokines

Cytokines & Growth Factors | EnkiLife - Empowering Life Science Research

What are Cytokines?

Cytokines are small proteins secreted by immune cells (such as monocytes, macrophages, T cells, B cells, NK cells, etc.) and certain non-immune cells (endothelial cells, epithelial cells, fibroblasts, etc.) upon stimulation. They regulate cell growth, differentiation, and effector functions, modulate immune responses, and participate in various physiological and pathological processes by binding to corresponding receptors.

Why Choose EnkiLife Cytokines?

Cytokines are pleiotropic immune regulators classified by receptor type that maintain homeostasis through complex networks; their imbalance drives immunopathogenesis and disease, making them key therapeutic targets. EnkiLife delivers reliable research tools using advanced expression and purification technologies, ensuring batch consistency, high bioactivity, and low endotoxin for every product.

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Product Categories

IL-1, IL-2, IL-3, IL-4, IL-6, IL-7, IL-12, IL-15, IL-18, etc. Key immunomodulatory molecules

TGF-β Superfamily

TGF-β, Activin, Inhibin, bone morphogenetic proteins (BMPs), and growth differentiation factors (GDFs)

IFN-α, IFN-β, IFN-γ, etc. Antiviral and immunomodulatory

CCL, CXCL, CX3CL subfamilies. Cell migration and positioning

TNF Superfamily

TNF-α, TNF-β, CD40L, FasL, etc. Apoptosis and survival

Colony Stimulating Factors

Four major members are recognized: granulocyte-macrophage CSF (GM-CSF), macrophage CSF (M-CSF/CSF-1), granulocyte CSF (G-CSF) and multipotential CSF (IL-3).

Vascular Endothelial Growth Factors

The vascular endothelial growth factor (VEGF) family comprises five secreted homodimeric glycoproteins—VEGF-A, VEGF-B, VEGF-C, VEGF-D and placental growth factor (PlGF)

Fibroblast Growth Factors

In humans, the FGF family includes 18 canonical members (FGF1–FGF10 and FGF16–FGF23), which are classified into six subfamilies based on sequence homology and functional characteristics

Insulin-like Growth Factors

The IGF family consists mainly of two low-molecular-weight protein (IGF-1 and IGF-2), the corresponding receptors (IGF-1R and IGF-2R) and specific binding proteins

TNFR Superfamily

The proteins of the tumor necrosis factor (TNF) receptor superfamily are a group of cell-surface receptors critically involved in the maintenance of homeostasis of the immune system

Interleukin Receptors

38 identified interleukins (IL-1 to IL-38) all need to bind to corresponding ILRs to exert their effects, and the specific binding between the two is the primary step for the realization of interleukin functions

Epidermal Growth Factors

EGFs bind to EGFR/ErbB family receptors, inducing dimerization and autophosphorylation

Stringent Quality Standards

≥95%

Purity by SDS-PAGE / SEC-HPLC

<1 EU/μg

Endotoxin Level

✓

Bioactivity Validated

GMP

Clinical-grade Manufacturing

Applications

Stem Cell Culture

SCF, Flt3L, LIF, BMPs maintain stem cell self-renewal and pluripotency, supporting iPSC, ESC, HSC culture

Immune Cell Differentiation

IL-2, IL-7, IL-15, GM-CSF induce T cell, NK cell, DC cell expansion and activation

Drug Screening

Standardized cytokines for high-throughput screening, accelerating drug discovery

Cell Therapy

GMP-grade products meet clinical application requirements, supporting CAR-T and NK cell therapy

Basic Research

Signal pathway studies, cell proliferation/differentiation mechanisms, disease model construction

Tissue Engineering

Growth factors promote 3D culture, organoid formation, and tissue repair research

Find the Ideal Cytokine for Your Research

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