ABCG2_RAT   Q80W57


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UniProt:Q80W57

Recommended name:Broad substrate specificity ATP-binding cassette transporter ABCG2 Curated

EC number:EC:7.6.2.2

Alternative names:ATP-binding cassette sub-family G member 2 Breast cancer resistance protein 1 homolog Urate exporter

Cleaved into:

GeneID:312382

Gene names  (primary ):Abcg2

Gene names  (synonym ):Bcrp1

Gene names  (ORF ):

Length:657

Mass:72,961

Sequence:MSSSNDHVLVPMSQRNKNGLPGMSSRGARTLAEGDVLSFHHITYRVKVKSGFLVRKTAEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPRGLSGDVLINGAPQPANFKCSSGYVVQDDVVMGTLTVRENLQFSAALRLPKAMKTHEKNERINTIIKELGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYFASAGYHCEPYNNPADFFLDVINGDSSAVMLNRGEQDHEANKTEEPSKREKPIIENLAEFYINSTIYGETKAELDQLPVAQKKKGSSAFREPVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLIVTVILGLIIGALYFGLKNDPTGMQNRAGVFFFLTTNQCFTSVSAVELFVVEKKLFIHEYISGYYRVSSYFFGKLVSDLLPMRFLPSVIYTCILYFMLGLKRTVEAFFIMMFTLIMVAYTASSMALAIAAGQSVVSVATLLMTISFVFMMLFSGLLVNLRTIGPWLSWLQYFSIPRYGFTALQHNEFLGQEFCPGLNVTMNSTCVNSYTICTGNDYLINQGIDLSPWGLWRNHVALACMIIIFLTIAYLKLLFLKKYS

Tissue specificity:Highly expressed in brain capillary, kidney and small intestine. Lower expression in heart. Preferentially expressed (at protein level) on the luminal membrane of brain capillaries, in kidney and small intestine. 2 s

Induction:

Developmental stage:Down-regulated upon ischemia-reperfusion. 1

Protein families:ABC transporter superfamily


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