SMS_RAT P60042
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UniProt:P60042
Recommended name:Somatostatin
EC number:
Alternative names:Antrin Somatostatin-28 Somatostatin-14 Neuronostatin 2 Publications (NST 1 Publication)
Cleaved into:
GeneID:24797
Gene names (primary ):Sst
Gene names (synonym ):Smst
Gene names (ORF ):
Length:116
Mass:12,746
Sequence:MLSCRLQCALAALCIVLALGGVTGAPSDPRLRQFLQKSLAAATGKQELAKYFLAELLSEPNQTENDALEPEDLPQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC
Tissue specificity:Somatostatin is detected in neurons throughout the brain, including in the lateral septum, nucleus accumbens, amygdaloid complex, hypothalamic periventricular nucleus, hippocampus, cortex, cerebellum and several brainstem nuclei (at protein level) (PubMed:20056135). Neuronostatin is widely expressed with highest levels in pleen and pancreas, followed by cerebrum and hypothalamus (at protein level) (PubMed:18753129, PubMed:26561648). Neuronostatin plasma levels are higher in fasted, as compared to fed animals (PubMed:26561648). In the brain, neuronostatin is mainly present in the hypothalamic periventricular nucleus and median eminence (at protein level) (PubMed:20056135). 3 s
Induction:
Developmental stage:
Protein families: