SMS_RAT   P60042


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UniProt:P60042

Recommended name:Somatostatin

EC number:

Alternative names:Antrin Somatostatin-28 Somatostatin-14 Neuronostatin 2 Publications (NST 1 Publication)

Cleaved into:

GeneID:24797

Gene names  (primary ):Sst

Gene names  (synonym ):Smst

Gene names  (ORF ):

Length:116

Mass:12,746

Sequence:MLSCRLQCALAALCIVLALGGVTGAPSDPRLRQFLQKSLAAATGKQELAKYFLAELLSEPNQTENDALEPEDLPQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC

Tissue specificity:Somatostatin is detected in neurons throughout the brain, including in the lateral septum, nucleus accumbens, amygdaloid complex, hypothalamic periventricular nucleus, hippocampus, cortex, cerebellum and several brainstem nuclei (at protein level) (PubMed:20056135). Neuronostatin is widely expressed with highest levels in pleen and pancreas, followed by cerebrum and hypothalamus (at protein level) (PubMed:18753129, PubMed:26561648). Neuronostatin plasma levels are higher in fasted, as compared to fed animals (PubMed:26561648). In the brain, neuronostatin is mainly present in the hypothalamic periventricular nucleus and median eminence (at protein level) (PubMed:20056135). 3 s

Induction:

Developmental stage:

Protein families:


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