HDGR2_RAT Q925G1
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UniProt:Q925G1
Recommended name:Hepatoma-derived growth factor-related protein 2
EC number:
Alternative names:Hepatoma-derived growth factor 3 (HDGF-3)
Cleaved into:
GeneID:
Gene names (primary ):Hdgfl2
Gene names (synonym ):Hdgf3, Hdgfrp2
Gene names (ORF ):
Length:669
Mass:74,018
Sequence:MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPLPVSSSDSEAPEADLGGGSDADKEKEARRVMTVTAVTTTATSGRTESDSDSDKNSDHSGLKRKTPVLKMSVSKRARKASSDLDQASVSPSEEDSESPSESEKTSDQDFTPEKKTIARAPRRAPLGGRKKKKVPSASDSDSRADSDGAKEEPVVTAQPSPSSSSSSSSSSASDSDVSIKKPPRGRKPAEKPPPKPRGRRSKPERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKERAERGGSSGEELEDEEPVKKRSRKARGRGTPSSSDSEPEGELGKEGKKLAKKSQLQGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLDRKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRRCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADGEKVEEQPGEQAPRELAEDEPSTDRSAPVNGEAASQKGENTEDGAQEDGQDLEDGPRGGSSEELHDSPQDSSDPARPGNEHQDHERMQLASESADDDDEDS
Tissue specificity:Expressed in the spinal cord (at protein level) (PubMed:26252862). Primarily restricted to neurons, astrocytes and oligodendrocytes and is particularly expressed in motor neurons of the anterior horn (at protein level) (PubMed:26252862). Significantly up-regulated in the injured spinal cord (at protein level) (PubMed:26252862). 1
Induction:
Developmental stage:Expressed at highest levels in the spinal cord at embryonic day 9, expression remains high at postnatal day 7 (P7), become weak at P14 and is not detectable at two months (at protein level). 1
Protein families: