HDGR2_RAT   Q925G1


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UniProt:Q925G1

Recommended name:Hepatoma-derived growth factor-related protein 2

EC number:

Alternative names:Hepatoma-derived growth factor 3 (HDGF-3)

Cleaved into:

GeneID:

Gene names  (primary ):Hdgfl2

Gene names  (synonym ):Hdgf3, Hdgfrp2

Gene names  (ORF ):

Length:669

Mass:74,018

Sequence:MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPLPVSSSDSEAPEADLGGGSDADKEKEARRVMTVTAVTTTATSGRTESDSDSDKNSDHSGLKRKTPVLKMSVSKRARKASSDLDQASVSPSEEDSESPSESEKTSDQDFTPEKKTIARAPRRAPLGGRKKKKVPSASDSDSRADSDGAKEEPVVTAQPSPSSSSSSSSSSASDSDVSIKKPPRGRKPAEKPPPKPRGRRSKPERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKERAERGGSSGEELEDEEPVKKRSRKARGRGTPSSSDSEPEGELGKEGKKLAKKSQLQGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLDRKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRRCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADGEKVEEQPGEQAPRELAEDEPSTDRSAPVNGEAASQKGENTEDGAQEDGQDLEDGPRGGSSEELHDSPQDSSDPARPGNEHQDHERMQLASESADDDDEDS

Tissue specificity:Expressed in the spinal cord (at protein level) (PubMed:26252862). Primarily restricted to neurons, astrocytes and oligodendrocytes and is particularly expressed in motor neurons of the anterior horn (at protein level) (PubMed:26252862). Significantly up-regulated in the injured spinal cord (at protein level) (PubMed:26252862). 1

Induction:

Developmental stage:Expressed at highest levels in the spinal cord at embryonic day 9, expression remains high at postnatal day 7 (P7), become weak at P14 and is not detectable at two months (at protein level). 1

Protein families:


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