PIM3_HUMAN   Q86V86


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UniProt:Q86V86

Recommended name:Serine/threonine-protein kinase pim-3

EC number:EC:2.7.11.1

Alternative names:

Cleaved into:

GeneID:415116

Gene names  (primary ):PIM3

Gene names  (synonym ):

Gene names  (ORF ):

Length:326

Mass:35891

Sequence:MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGVPESCDLRLCTLDPDDVASTTSSSESL

Tissue specificity:Detected in various tissues, including the heart, brain, lung, kidney, spleen, placenta, skeletal muscle, and peripheral blood leukocytes. Not found or barely expressed in the normal adult endoderm-derived organs such as colon, thymus, liver, or small intestine. However, expression is augmented in premalignant and malignant lesions of these organs. {ECO:0000269|PubMed:15540201, ECO:0000269|PubMed:16818649, ECO:0000269|PubMed:17270021}.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PIM subfamily


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