TRYB1_HUMAN   Q15661


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UniProt:Q15661

Recommended name:Tryptase alpha/beta-1

EC number:EC:3.4.21.59

Alternative names:(Tryptase-1) (Tryptase I) (Tryptase alpha-1)

Cleaved into:

GeneID:7177

Gene names  (primary ):TPSAB1

Gene names  (synonym ):TPS1 TPS2 TPSB1

Gene names  (ORF ):

Length:275

Mass:30515

Sequence:MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP

Tissue specificity:Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level). {ECO:0000269|PubMed:18854315}.

Induction:

Developmental stage:

Protein families:Peptidase S1 family, Tryptase subfamily


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