TRYB1_HUMAN Q15661
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UniProt:Q15661
Recommended name:Tryptase alpha/beta-1
EC number:EC:3.4.21.59
Alternative names:(Tryptase-1) (Tryptase I) (Tryptase alpha-1)
Cleaved into:
GeneID:7177
Gene names (primary ):TPSAB1
Gene names (synonym ):TPS1 TPS2 TPSB1
Gene names (ORF ):
Length:275
Mass:30515
Sequence:MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
Tissue specificity:Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level). {ECO:0000269|PubMed:18854315}.
Induction:
Developmental stage:
Protein families:Peptidase S1 family, Tryptase subfamily