KAPCB_HUMAN P22694
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UniProt:P22694
Recommended name:cAMP-dependent protein kinase catalytic subunit beta
EC number:EC:2.7.11.11
Alternative names:(PKA C-beta)
Cleaved into:
GeneID:5567
Gene names (primary ):PRKACB
Gene names (synonym ):
Gene names (ORF ):
Length:351
Mass:40623
Sequence:MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
Tissue specificity:Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain. {ECO:0000269|PubMed:11589697}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily