TYOBP_HUMAN   O43914


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UniProt:O43914

Recommended name:TYRO protein tyrosine kinase-binding protein

EC number:

Alternative names:(DNAX-activation protein 12) (Killer-activating receptor-associated protein) (KAR-associated protein)

Cleaved into:

GeneID:7305

Gene names  (primary ):TYROBP

Gene names  (synonym ):DAP12 KARAP

Gene names  (ORF ):

Length:113

Mass:12179

Sequence:MGGLEPCSRLLLLPLLLAVSGLRPVQAQAQSDCSCSTVSPGVLAGIVMGDLVLTVLIALAVYFLGRLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK

Tissue specificity:Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Expressed in hematological cells and tissues such as peripheral blood leukocytes and spleen. Also found in bone marrow, lymph nodes, placenta, lung and liver. Expressed at lower levels in different parts of the brain especially in the basal ganglia and corpus callosum. {ECO:0000269|PubMed:11922939}.

Induction:

Developmental stage:

Protein families:TYROBP family


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