I5P1_HUMAN   Q14642


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UniProt:Q14642

Recommended name:Inositol polyphosphate-5-phosphatase A

EC number:EC:3.1.3.56

Alternative names:(43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)

Cleaved into:

GeneID:3632

Gene names  (primary ):INPP5A

Gene names  (synonym ):5PTASE

Gene names  (ORF ):

Length:412

Mass:47820

Sequence:MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGKPHAHVHKCCVVQ

Tissue specificity:Predominantly expressed in heart, brain, and skeletal muscle (PubMed:8006039). In brain; high level in Purkinje cells (PubMed:8013665). {ECO:0000269|PubMed:8006039, ECO:0000269|PubMed:8013665}.

Induction:

Developmental stage:

Protein families:Inositol 1,4,5-trisphosphate 5-phosphatase type I family


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