AK1A1_HUMAN P14550
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UniProt:P14550
Recommended name:Aldo-keto reductase family 1 member A1
EC number:EC:1.1.1.2
Alternative names:(Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (Glucuronolactone reductase)
Cleaved into:
GeneID:10327
Gene names (primary ):AKR1A1
Gene names (synonym ):ALDR1 ALR
Gene names (ORF ):
Length:325
Mass:36573
Sequence:MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY
Tissue specificity:Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung. {ECO:0000269|PubMed:10486210, ECO:0000269|PubMed:10510318, ECO:0000269|PubMed:11306097}.
Induction:
Developmental stage:
Protein families:Aldo/keto reductase family