RAI3_HUMAN Q8NFJ5
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UniProt:Q8NFJ5
Recommended name：Retinoic acid-induced protein 3
EC number：
Alternative names：(G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1)
Cleaved into：
GeneID：9052
Gene names (primary )：GPRC5A
Gene names (synonym )：GPCR5A RAI3 RAIG1
Gene names (ORF )：
Length：357
Mass：40251
Sequence：MATTVPDGCRNGLKSKYYRLCDKAEAWGIVLETVATAGVVTSVAFMLTLPILVCKVQDSNRRKMLPTQFLFLLGVLGIFGLTFAFIIGLDGSTGPTRFFLFGILFSICFSCLLAHAVSLTKLVRGRKPLSLLVILGLAVGFSLVQDVIAIEYIVLTMNRTNVNVFSELSAPRRNEDFVLLLTYVLFLMALTFLMSSFTFCGSFTGWKRHGAHIYLTMLLSIAIWVAWITLLMLPDFDRRWDDTILSSALAANGWVFLLAYVSPEFWLLTKQRNPMDYPVEDAFCKPQLVKKSYGVENRAYSQEEITQGFEETGDTLYAPYSTHFQLQNQPPQKEFSIPRAHAWPSPYKDYEVKKEGS
Tissue specificity：Expressed at high level in fetal and adult lung tissues but repressed in most human lung cancers (PubMed:9857033, PubMed:18000218). Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to PubMed:10783259, expressed at low but detectable level in pancreas and heart. {ECO:0000269|PubMed:10783259, ECO:0000269|PubMed:10945465, ECO:0000269|PubMed:18000218, ECO:0000269|PubMed:9857033}.
Induction：By all-trans retinoic acid (ATRA). {ECO:0000269|PubMed:9857033}.
Developmental stage：
Protein families：G-protein coupled receptor 3 family