CLC2A_HUMAN   Q6UVW9


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UniProt:Q6UVW9

Recommended name:C-type lectin domain family 2 member A

EC number:

Alternative names:(Keratinocyte-associated C-type lectin) (KACL) (Proliferation-induced lymphocyte-associated receptor) (PILAR)

Cleaved into:

GeneID:387836

Gene names  (primary ):CLEC2A

Gene names  (synonym ):KACL

Gene names  (ORF ):UNQ5792/PRO19597

Length:174

Mass:19972

Sequence:MINPELRDGRADGFIHRIVPKLIQNWKIGLMCFLSIIITTVCIIMIATWSKHAKPVACSGDWLGVRDKCFYFSDDTRNWTASKIFCSLQKAELAQIDTQEDMEFLKRYAGTDMHWIGLSRKQGDSWKWTNGTTFNGWFEIIGNGSFAFLSADGVHSSRGFIDIKWICSKPKYFL

Tissue specificity:Mainly expressed in skin. Also expressed in keratinocytes, spleen, thymus, small intestine, peripheral blood monocytes, bone marrow, ovary, testis and skin. High expression in CD8(+), B-lymphocytes and naive CD4(+) T-cells. Restricted mostly to proliferating lymphocytes. Not detected in myeloid leukocytes or natural killer (NK) cells. {ECO:0000269|PubMed:18046548, ECO:0000269|PubMed:18550855, ECO:0000269|PubMed:20194751}.

Induction:By phytohemagglutinin (PHA) in peripheral CD8(+) T cells.

Developmental stage:

Protein families:


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