PPARA_HUMAN Q07869
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UniProt:Q07869
Recommended name:Peroxisome proliferator-activated receptor alpha
EC number:
Alternative names:(PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1)
Cleaved into:
GeneID:5465
Gene names (primary ):PPARA
Gene names (synonym ):NR1C1 PPAR
Gene names (ORF ):
Length:468
Mass:52225
Sequence:MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
Tissue specificity:Skeletal muscle, liver, heart and kidney. Expressed in monocytes (PubMed:28167758). {ECO:0000269|PubMed:28167758, ECO:0000269|PubMed:7981125, ECO:0000269|PubMed:8993548}.
Induction:Down-regulated by aging. {ECO:0000269|PubMed:28167758}.
Developmental stage:
Protein families:Nuclear hormone receptor family, NR1 subfamily